BDBM443221 N-(2-((6-(3-(2,6-Dichloro-3,5-dimethoxyphenyl)-1-methylureido)pyrimidin-4-yl)amino)-5-(4,7-diazaspiro[2.5]octan-7-yl)phenyl)acrylamide::US10654836, Example 2::US11001572, Example 2
SMILES COc1cc(OC)c(Cl)c(NC(=O)N(C)c2cc(Nc3ccc(cc3NC(=O)C=C)N3CCNC4(CC4)C3)ncn2)c1Cl
InChI Key InChIKey=AMWFCWPVINFBES-UHFFFAOYSA-N
Data 8 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 443221
Affinity DataIC50: 4.60nMAssay Description:The following method was used to determine the inhibition degree of the kinase activity of recombinant human FGFR protein by the compounds of the pre...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:The experimental procedure is briefly described as follows: the test compound was first dissolved in DMSO to prepare a stock solution, and then gradi...More data for this Ligand-Target Pair